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La irrupci n del invierno en el
2019-05-29
La irrupción del invierno en el “lugar que fue nuestro” es un motivo de lamentación melancólica porque estorba la dicha del yo lírico. La llegada de la nueva temporada se expresa con una referencia explícita al comienzo del invierno en el primer verso y una evocación de “las bandadas que emigran”. E
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br Es curioso observar que en
2019-05-29
Es curioso observar que en el terreno de la crítica musical, la tarea fundamental es evidentemente depurar la teoría de todo aquello que obstaculiza la formulación precisa de los elementos esenciales de la música. Sin embargo, cuando se trata de estudiar el tema de la música en la literatura, nada
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Recently emerging data suggest that lower frequency of
2019-05-28
Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f
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br Results Compared to the respective untreated groups the V
2019-05-28
Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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MCs play a key role in the maintaining homeostasis
2019-05-28
MCs play a key role in the maintaining homeostasis of tissues where they reside by participating in tissue repair, reactions against viral and parasitic infections, and aiding in the regulation of various cell types such as dendritic cells, T cells, and macrophages. In addition, MCs are involved in
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Villoro cuestiona la forma incorrecta en que es
2019-05-28
Villoro cuestiona la forma incorrecta en que es presentada la relación entre estos derechos como dos sujetos confrontados, en tanto que opina que no existe un sujeto colectivo en el mismo sentido que lo es el sujeto individual, sólo éste es intencional, el colectivo no es un ente que exista sin la p
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Expresi n de la complejidad de esta articulaci n de
2019-05-28
Expresión de la complejidad de esta articulación de los movimientos de la región en este proyecto es, además, la gestación —de forma paralela no one care los cms, desde 2009— de la Articulación Continental de Movimientos Sociales hacia el alba, cuyo punto de partida es la “Carta de los Movimientos S
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La expedici n colombiana de Preuss fue patrocinada por
2019-05-28
La expedición colombiana de Preuss fue patrocinada por la fundación que Joseph Florimont, duque de Loubat, había establecido para la Cátedra de Lingüística, Arqueología y Etnología Americanas. Igual que la Expedición al Nayarit (1905-1907), el viaje hydroxylase inhibitor Colombia (1913-1919) combina
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Cardiac fibroblasts express various ion channels in
2019-05-28
Cardiac fibroblasts express various ion channels, in particular voltage-gated K Dynasore and nonselective cation channels of the transient receptor potential (TRP) family . Both K and TRP channels are important determinants of fibroblast function, with TRP channels acting as Ca entry pathways that s
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The benign exostoses in TRPS have a
2019-05-28
The benign exostoses in TRPS have a recognized malignant potential which have been shown to develop into chondrosarcomas [4,13]. Both our index case and his mother demonstrated de novo high grade osteosarcoma. To our knowledge, this occurrence has not been described anywhere within the literature.
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Our results are consistent with previous findings in
2019-05-28
Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].
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Atrial fibrosis is one of the fundamental mechanisms
2019-05-27
Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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The authors of the NCCN non small cell
2019-05-27
The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w
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The tumor microenvironment is enriched with
2019-05-27
The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma
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Pain flare defined as a temporary
2019-05-27
Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte
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