• The authors of the NCCN non small cell

  2019-05-27

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• The tumor microenvironment is enriched with

  2019-05-27

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• Pain flare defined as a temporary

  2019-05-27

  

  Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte

• X rays commonly show a

  2019-05-27

  

  X-rays commonly show a typical licked candy stick appearance, based on concentric bone resorption. Common blood tests are usually normal, but bone alkaline phosphatase (BAP) may be elevated if a fracture occurred [8]. GSD is a diagnosis of exclusion. Diseases responsible of bone osteolysis such as i

• Feeding stimulates gallbladder contraction emptying its cont

  2019-05-27

  

  Feeding stimulates gallbladder contraction, emptying its contents into the upper part of the small intestine, where CBAs activate pancreatic lipase to release monoglycerides and free fatty acids from triglycerides. Mixed micelles with monoglycerides, fatty acids, cholesterol, and fat-soluble vitamin

• The distribution of dental treatments and the number of

  2019-05-27

  

  The distribution of dental treatments and the number of treated teeth within each age group were also analyzed. The  6-years-old group had the lowest mean number of teeth treated by stainless-steel crown (SSC) and the lowest number undergoing pulp therapy (pa01 and, when compared against 2015, ther

• Because of the high amplitude

  2019-05-27

  

  Because of the high amplitude of atrial signals, atrial sensitivity was decreased from 0.5mV to 0.7mV to 1.0mV. As the sensitivity decreased, atrial sensing was restored gradually. With the sensitivity of 1.0mV, normal atrial sensing with mode switching was restored completely. The sensitivity was p

• Sulindac sulfide People in LMICs are disproportionately expo

  2019-05-24

  

  People in LMICs are disproportionately exposed to severe acute kidney injury and have substantially less access to effective treatment than do people in higher-income countries. Framing acute kidney injury as a driver of substantial inequity in disease risk and mortality in low-resource countries, t

• br Sensors for HF monitoring can be

  2019-05-24

  

  Sensors for HF monitoring can be classified according to the technical instrumentation. Table 2 summarizes the sensors that have been used or proposed to monitor the events of HF. The paced QRS enables the determination of the QT duration. In addition, the QRS width, measured as the ventricular de

• It means an opportunity As we concern

  2019-05-24

  

  It means an opportunity. As we concern ourselves with the prominence of health in the new agenda, it\'s easy to forget that (human) development is by definition people-centred, and that living a long, healthy, and creative life is its cornerstone. The expansion of the new goals to encompass many (if

• Importa notar al mismo tiempo cierta impaciencia con la inde

  2019-05-24

  

  Importa notar, al mismo tiempo, cierta impaciencia con la indeterminación del saber celebrada hasta no hace mucho. En la ruta hacia el neoliberalismo, ese tránsito del Estado al mercado —como suele llamársele en América Latina—, la duda epistémica, el pensamiento débil, los juegos de lenguaje y la r

• Qu dicen las fechas en que se ha

  2019-05-24

  

  ¿Qué dicen las fechas en que se ha flexibilizado la posición de ambas partes? Veamos una cita elocuente sobre la situación internacional en la década de los años setenta del siglo pasado, marco en el que se mejoraron las relaciones entre Washington y La Habana, bajo el gobierno de James Carter. Por

• Al concluir las deliberaciones el congreso resolvi apoyar la

  2019-05-24

  

  Al concluir las deliberaciones, el congreso resolvió apoyar las gestiones de los gobiernos de “Argentina, Guatemala, Uruguay, Paraguay, Chile y Bolivia por su valiente postura de no dejarse intimidar, ni por las amenazas difamatorias en su contra, ni por las presiones y amenazas del ‘cartercomunismo

• br Should child growth replace

  2019-05-24

  

  Should child growth replace diarrhoea as the primary child health outcome for sanitation trials? We appreciate Derek Headey\'s comment in relation to our trial that the window of opportunity to plausibly affect growth faltering is from in utero up to 24 months, and therefore that sanitation trials

• br Discussion Sato et al first

  2019-05-24

  

  Discussion Sato et al. [11] first reported TCM in 1990, and thereafter, numerous cases were reported in the late 2000s. In 85% of the cases, TCM onset was preceded by an emotional or physical stress event, however, in 15% of the cases, the presence of a stress trigger could not be detected [2]. M

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