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The goals of Vision the global initiative
2019-04-23
The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communit
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Haemorrhagic stroke was once a major cause
2019-04-23
Haemorrhagic stroke was once a major cause of death in high-income nations, but its importance has receded in those regions over the 20th century. Our results suggest that, in the first decade of the 21st century, haemorrhagic stroke remains an important cause of death and disability worldwide. With
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Air pollution also has a substantial effect on the
2019-04-23
Air pollution also has a substantial effect on the wellbeing of people worldwide. This pollution can consist of sulfur dioxide, ozone, nitrogen dioxide, and fine-particulate prostaglandin endoperoxide synthase of less than 2·5 μm in diameter (PM). 92% of the global population is exposed to higher-t
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br After several decades of community based interventions
2019-04-23
After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked
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Human p MAPK is stimulated by various inflammatory cytokines
2019-04-23
Human p38 MAPK is stimulated by various inflammatory cytokines and cellular stresses [46]. Especially, the p38 MAPK signaling pathway is a crucial modulator of proinflammatory cytokine biosynthesis at the transcriptional and translational levels [46]. Furthermore, studies revealed that p38 MAPK regu
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br Introduction Acute myeloid leukemia AML remains a hematol
2019-04-22
Introduction Acute myeloid leukemia (AML) remains a hematologic malignancy with poor outcome and a high risk for relapse believed to be caused by the survival of leukemic stem cells (LSCs), which are responsible for disease repopulation following treatment [1]. This important implication of LSCs
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An ERP in the ECG has
2019-04-22
An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A
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More recently Brugada et al used flecainide
2019-04-22
More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial
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Moving forward we identify several urgent
2019-04-22
Moving forward, we identify several urgent needs and challenges. First, the standing of estrogen related receptor health workers in the health-care systems needs to be legitimised and moved away from largely grant-funded temporary employees or volunteers who might provide educational services towar
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br Hematopoietic cell transplantation HCT is generally recom
2019-04-22
Hematopoietic cell transplantation HCT is generally recommended for AML patients with intermediate or high risk cytogenetics, when the aim of treatment is curative. However, elderly patients are seldom offered a transplant mainly due to concerns regarding toxicity, despite the fact that the main
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br A few years ago my group published an
2019-04-22
A few years ago, my group published an article entitled uhuru. is the Swahili word for “freedom”. The idea was to highlight the plight of patients with end-stage kidney disease (ESKD) and the challenges and frustrations of their nephrologists in sub-Saharan Africa amidst health-care authorities th
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Patients were divided randomly into two groups at
2019-04-22
Patients were divided randomly into two groups at the time of hCG administration. Patients in Group 1 (n = 38; 33.6%) underwent IUI 24 hours after hCG administration. Group 2 (n = 75; 66.4%) underwent IUI 36 hours after hCG administration. All patients were instructed to have intercourse when the do
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Con frecuencia el tratamiento de la fauna en Indias no
2019-04-20
Con frecuencia el tratamiento de la Rimonabant en Indias no es muy diferente; el bestiario que pudiera emerger de las crónicas abarca una fauna en la que la mirada acentúa lo diferente y lo exótico, el mito y la leyenda, pero ante todo se expresa y plasma en una estética en la que van juntos el top
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br Commentary Recordings of the
2019-04-20
Commentary Recordings of the activation sequence from the CS during tachycardia are expected to help discriminate among atrial tachyarrhythmias [2]. During ongoing typical CCW AFL, most of the CS is activated from proximal to distal, because the CS musculature, by being continuous with the RA myo
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br Introduction Magnetic resonance imaging
2019-04-20
Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) is that you sometimes does not allow differentiatio
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