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br Materials and methods Male
2019-09-21
Materials and methods Male Hartley guinea pigs (300–350g) were obtained from National Laboratory Animal Center, Taiwan. LTD4, LTC4, LTE4, LTB4, montelukast and BAY u9773 were purchased from Cayman Chemical, Ann Arbor, Michigan; Carbachol, atropine, l-serine, boric acid, l-cysteine and all buffer
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AP 24534 Converging evidence suggests that reduced glutamate
2019-09-21
Converging evidence suggests that reduced glutamate transmission in the LS is linked to increased anxiety-like behaviors (Radulovic et al., 1999, Henry et al., 2006, Bakshi et al., 2002, Liu et al., 2004). Therefore, attenuated CRF1 receptor-mediated excitatory transmission in the LS following ASV-t
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The underlying assumption of consolidation
2019-09-20
The underlying assumption of consolidation/re-consolidation is that the TRAM 39 activity initiated during the acquisition trial/re-consolidation trial continues to persist briefly after completion of the trial and it is during this post-trial period that immediate post-trial treatments can influenc
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br Introduction Mammalian proteases comprise both
2019-09-20
Introduction Mammalian proteases comprise both the peptidases or exopeptidases, which act at the N- or C-terminal positions of polypeptides, and proteinases or endopeptidases, which are capable of cleaving peptide bonds in the central regions of polypeptides. The endopeptidases are classified in
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The majority of serpins inhibit serine
2019-09-20
The majority of serpins inhibit serine proteases, but serpins that inhibit caspases or papain-like cysteine proteases have also been identified [4], [5]. Inhibitory serpins are ‘suicide’ or ‘single use’ inhibitors that use a unique conformational change to inhibit proteases. This conformational tran
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br Synthesis and mechanism of fluorescent DNA CuNMs br Appli
2019-09-20
Synthesis and mechanism of fluorescent DNA-CuNMs Application of fluorescent DNA-CuNMs Summary and conclusions In summary, we introduce recent research progress in the synthesis and various applications of DNA-CuNMs. DNA-CuNMs with novel catalytic, electrical and optical properties can be o
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br Acknowledgements br Introductio http www
2019-09-20
Acknowledgements Introduction TB is also widely prescribed as a stain to identify proteoglycans and glycosaminoglycans (GAGs) in agarose gel electrophoresis (Dietrich and Dietrich, 1976; Coulson-Thomas et al., 2015). In addition, as adjunct to a photodynamic antimicrobial chemotherapy assay, T
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br Results br Discussion MSCs derived from the bone marrow
2019-09-20
Results Discussion MSCs derived from the bone marrow and adipose tissue have been shown to promote the growth and metastatic ability of breast cancer and other human malignancies, but the mechanisms are incompletely understood (Barcellos-Hoff et al., 2013, Cuiffo et al., 2014, Del Pozo Martin
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Two in vitro reports using lung fibroblasts have shown
2019-09-20
Two in vitro reports using lung fibroblasts have shown that cell transmigration, using transwell migration experiments, through collagen I-coated inserts is mediated by DDR2 and the DDR2-associated signaling kinases JAK2 and ERK1/2, but not DDR1 [63] and that DDR2 regulates the adhesion of fibroblas
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br Chagas disease Chagas disease an NTD
2019-09-20
Chagas disease Chagas disease, an NTD caused by the protozoan Trypanosoma cruzi, affects 8–10 million people globally. More than 10,000 deaths are caused by the disease each year, and nearly 70 million people are susceptible to infection (Manne-Goehler, Umeh, Montgomery, & Wirtz, 2016). Chagas di
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Some of the psychoactive actions
2019-09-20
Some of the psychoactive actions of nicotine are mediated by the nigrostriatal and mesolimbic pathways (Di Chiara, 2000, Di Chiara et al., 2004). The nigrostriatal pathway originates in the dopaminergic neurons located in the substantia nigra and terminates in the putamen and nucleus caudatus which
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The proposed FDIR technique is presented in the
2019-09-20
The proposed FDIR technique is presented in the following format: Section 2 contains a survey of typical orbits of interest with regard to the cytochalasin d environment found in them, which is contrasted with a LEO orbit. Additionally, how the requirements for the satellite system can be estimated
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lcz696 mass Cell swelling stimulates the release
2019-09-20
Cell swelling stimulates the release of certain amino acids, in particular the non-protein amino lcz696 mass taurine, via a pathway which has the characteristics of a channel rather than a carrier [54], [69]. Indeed, on the basis of pharmacological inhibition, it was suggested that volume-activated
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It was reported that IVM modulates
2019-09-20
It was reported that IVM modulates various ion channels, such as type-A GABACls, α7 acetylcholine-gated cation channels, P2X4 ATP-gated cation channels, and glycine-gated chloride NLG919 in vertebrates (Adelsberger et al., 2000, Khakh et al., 1999, Krause et al., 1998, Krůšek and Zemková, 1994, Sha
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Evidence for interactions between the endothelin and
2019-09-20
Evidence for interactions between the endothelin and the angiotensin system has also become plentiful. It has become clear that the two systems, in addition to acting independently, can act synergistically (Emori et al., 1989, Imai et al., 1992) as well as promote the peptide mRNA expression in endo
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