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Cholangiopathies are a group of rare diseases
2019-04-19
Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce
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The great American epidemiologist Bill Silverman taught
2019-04-19
The great American epidemiologist Bill Silverman taught us that the road to hell is paved with good intentions. From 1942, during a 12-year period, more than 10 000 infants were blinded through retinopathy of prematurity because paediatricians recommended a minor increase in the concentration of sup
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Sin embargo la Relaci n no fue traducida en
2019-04-19
Sin embargo, la Relación no fue traducida en forma igualmente precisa por Ulloa, que nos devuelve un texto corrompido, lo cual se manifiesta en las transcripciones de los términos en la lengua indígena. Por fortuna, es posible comparar el texto italiano con otras versiones producidas durante la prim
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While resistance to imatinib is rare in patients
2019-04-18
While resistance to imatinib is rare in patients treated in CML-CP, resistance does eventually develop in the majority of patients treated in the advanced phases. In a high proportion of patients who develop secondary resistance after initial responses, point mutations in the BCR-ABL kinase domain h
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We read with great interest the article
2019-04-18
We read with great interest the article entitle “Chronic lymphocytic lymphoma and concomitant renal cell carcinoma (Clear Cell Type): Review of the literature”, written by Uz et al. and published in a recent issue of your journal. Here, we would like to emphasize some points about this review of the
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tak1 inhibitor Data on chloroquine resistance from
2019-04-18
Data on chloroquine resistance from Pakistan is scarce, even in the most recent global analysis. Nevertheless, in 2013, the emergence of the F1076L mutant of the gene—the tak1 inhibitor responsible for chloroquine resistance—in in Pakistan highlights the imminent threat of resistant . In 2015, th
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Many of the emerging non vaccine serotypes in carriage after
2019-04-18
Many of the emerging non-vaccine serotypes in carriage after PCV13 implementation (11A, 15B/C, 15A, 21, 23B, and 35F) show low potential for causing invasive disease, but some—eg, 12F, 22F, 24F, 8, and 9N—have high disease potential. Moreover, in vulnerable populations (eg, immunocompromised people)
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purchase Dynasore br Discussion The presence of metastases a
2019-04-18
Discussion The presence of metastases at the time of diagnosis is a significant prognostic factor in osteosarcoma [14]. Skeletal metastases at time of presentations appears to carry a worse prognosis than pulmonary metastases [15]. Furthermore, the chance of survival can be improved by surgical r
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Patients with syncope often suffer secondary trauma Major mo
2019-04-18
Patients with syncope often suffer secondary trauma. Major morbidities such as fractures and injuries from motor vehicle accidents have been reported in 6% of patients, whereas minor injuries such as lacerations and bruises have been reported in 29% [1]. Recurrent syncope was associated with fractur
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Durrer et al reported that ventricular depolarization begins
2019-04-18
Durrer et al. [17] reported that ventricular depolarization begins in the LV septum, which suggests that initiating pacing from regions close to this area (e.g., RV septum) may produce a physiologic contraction pattern. In contrast, the free wall of the RV is the last zone to be depolarized. Thus, i
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Close inspection of the tumor
2019-04-18
Close inspection of the tumor matrix on the initial and subsequent 5 month radiographs (Fig. 7), shows an atypical appearance for osteoid matrix that Sunitinib manufacturer may more closely resemble chondroid matrix. The matrix appears to display a linear dense lace-like pattern (Fig. 8). Of the on
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An enhanced T wave suppression mode
2019-04-18
An enhanced T wave suppression mode was very effective to manage TWOS and was able to detect induced and spontaneous VF correctly. On the other hand, it has been reported that Biotronik devices connected to integrated bipolar ICD leads from other manufacturers had an increased risk for oversensing [
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La descripci n arquitect nica de
2019-04-17
La descripción arquitectónica de la quinta es heterogénea, extensa, precisa, sugerente, sin duda uno de los pasajes en El fistol del diablo más revisados y pulidos por Payno, con la totalidad de la novela en mente, por lo tanto pleno de simbolismo histórico-cultural y de presagios. Por principio, el
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Much of the focus of expert
2019-04-17
Much of the focus of expert and public attention has been on HIV treatment, including test and treat (ie, treatment as prevention) strategies. This is understandable. Treatment for HIV has become extraordinarily effective, costs have dropped substantially during the past two decades, and the potenti
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br Conflict of Interest br
2019-04-17
Conflict of Interest Acknowledgments The authors acknowledge grant from Department of Atomic Energy (DAE), Govt. of India, Grant number: 2013/35/45/BRNS and the technical support of the MSSB (Molecular Stress and Stem Cell Biology) group, School of Biotechnology. We would also like to thank Dr
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