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Another representative clinical case associated with disrupt
2018-11-15
Another representative clinical case associated with disruption of this remodeling is recessive X-linked ichthyosis (MIM 30810), which is characterized by generalized hyperkeratosis, showing large dark brown scales predominantly on both the extensors. This disease demonstrates characteristic histopa
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Some studies reported an increased risk
2018-11-15
Some studies reported an increased risk of anxiety and depression in acne vulgaris patients accompanied by an impairment of quality of life in comparison with healthy individuals, although some studies showed no difference. In this study, we evaluated the quality of life with an acne-specific index,
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br Bowen s disease BD also known as
2018-11-15
Bowen’s disease (BD), also known as squamous cell carcinoma, may occur at any skin site; however, the involvement of the palmer aspect is rare. Skin lesions of BD typically present as a scaly erythematous plaque, whereas BD of the palms shows an atypical appearance. We herein present a case of mu
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br Reactive metals and metal
2018-11-15
Reactive metals and metal carbonyls Yen and Wang reviewed several lipid metabolism pathway of reactive metals that have been considered for energetic applications [2]. These include elemental metals, thermites/intermolecular composites (MIC), encapsulated metals, metastable alloys and “surface a
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In this report we give the full
2018-11-15
In this report, we give the full accounts of the detailed synthesis of 2-halo-6-amino or 6-hydroxyamino-2′-deoxy-2′-methylideneadenosine derivatives (Schemes 1 and 2). Results and discussion Methodology Introduction Molybdenum hydroxylases are group of enzymes that share the transition met
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Reported drawbacks of the LTD were enhanced
2018-11-15
Reported drawbacks of the LTD were enhanced wear rates [11] with loss of small surface zirconia grains in the surrounding environment causing an increase in surface roughness and surface uplifts with both mechanical [12] and esthetic worsening [10]. Although hundreds of laboratory researches dealt
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Further EVA focuses on short
2018-11-15
Further, EVA focuses on short term gains and immediate results that deter managers to invest their time and effort in innovative products and processes. Since costs associated with R&D in projects are immediately recognized, at least in part, by accountants, their benefits accrue to an organization
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Introduction A great variation in nursing homes exists acros
2018-11-14
Introduction A great variation in nursing homes exists across the world. In general, nursing homes provide an alternative place of residence, where 24-h care and assistance is offered by professional caregivers when people can no longer reside in their own home environment due to increasing need fo
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br A proposed two stage framework This comparativeanalysis o
2018-11-14
A proposed two-stage framework This comparativeanalysis of the entrants to a NS-398 in the U.S. provides new insight as to how EBR&D can be woven into the fabric of future competitions. Kaiser Permanente, one of the leading healthcare providers as well as innovators in the U.S. healthcare industr
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br Results The results showed a correlation
2018-11-14
Results The results showed a correlation between demographic groups and method of choice or perception of graphic quality. Age was a factor in preference of tool use (hand, digital, or a hand/digital hybrid approach) in the creation of design sketches (Χ2 (10)=25.411, p=.005) and for illustrative
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The Wnt catenin pathway can
2018-11-14
The Wnt/β-catenin pathway can also activate somatic cell reprogramming to pluripotency. Mouse embryonic fibroblasts (MEFs) transduced with retroviruses carrying Oct4, Klf4, and Sox2 and cultured in medium containing Wnt3a can generate induced pluripotent stem cell (iPSC) colonies with enhanced effic
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The device generates probing ultrasonic waves
2018-11-14
The device generates probing ultrasonic waves [7] (one longitudinal and two transverse, polarized in mutually perpendicular directions) by piezoelectric transducers (PETs) serving as piezo-actuators. The reflected elastic waves excited in the material of the controlled object are also received by th
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Alternatively the elastic wave velocities
2018-11-14
Alternatively, the elastic wave velocities (Vs and Vp in km/s) of the Rw at certain P-T condition can be readily calculated by using its corresponding shear modulus (G; GPa), adiabatic bulk modulus (KS; GPa) and density (ρ; g/cm3), according to the following equations:and With its G0, KS0 and ρ0 (G
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A pharmacometabolomics aided pharmacogenomics workflow inclu
2018-11-14
A “pharmacometabolomics-aided pharmacogenomics” workflow includes sample acquisition and preparation, analysis (NMR or mass spectrometry technologies), data processing and data analysis (targeted and non-targeted) (Mussap et al., 2013). For those familiar with (pharmaco)metabolomics approaches, such
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Interestingly dataset analyses show that HK
2018-11-14
Interestingly, dataset analyses show that HK2 is highly expressed in CRPC compared to the primary prostate cancer. Our findings thus provide preclinical proof-of-concept that co-targeting Warburg effect with 2-DG and autophagy with CQ could be extended to effectively treat CRPC patients whose tumors
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