• br Discussion It is generally known

  2019-06-29

  

  Discussion It is generally known that primary CNS melanomas are rare and difficult to diagnose prior to biopsy. According to tumor melanin content, four subtypes of malignant intracranial melanoma have been proposed, associated with different MRI image presentations. These subtypes are: 1) melano

• In the current era nearly all cases of

  2019-06-29

  

  In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud

• Both breast cancer and MM cause osteolytic lesions inhibitin

  2019-06-29

  

  Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit

• A major development during was

  2019-06-29

  

  A major development during 2015 was that OCV demand exceeded supply (). The main reasons for this increase in demand are the observed feasibility of mass OCV campaigns and their ability to confer protection to underserved populations in complex situations. The increased availability and use of OCV

• Our investigation suggests that cardiac pacing improves

  2019-06-29

  

  Our investigation suggests that cardiac pacing improves not only CSA but also OSA. The mechanism by which SDB is improved is unclear. CSA might be improved by reduction of periodic variations in heart rate, which are increased by Fluticasone propionate and may result in part from changes in autonom

• Es un hecho innegable que la descripci n que

  2019-06-28

  

  Es un hecho innegable que la descripción que Servando Teresa de Mier plasma en sus Memorias (escritas en las cárceles inquisitoriales de Nueva España entre 1818 y 1820) sobre su estadía forzada en Europa por más de veinte años presenta exageraciones sobre el castigo que la Inquisición española le im

• En producto de un seminario

  2019-06-28

  

  En 1971, producto de un seminario organizado por Norbert Lechner, Hinkelammert escribe un artículo titulado “La situación de la sexualidad dentro del materialismo histórico.” ¿Por qué, Omecamtiv mecarbil molecular pesar de sus contradicciones, el capitalismo “no explota en una crisis final”?, ¿cómo

• br Mechanisms of arrhythmias Several schemes

  2019-06-28

  

  Mechanisms of arrhythmias Several schemes have been used to classify the mechanisms of cardiac arrhythmias. Traditionally, these have been divided into nonreentrant and reentrant activity [11]. An alternative scheme divided them into those occurring at the cellular and tissue levels [12]. A dynam

• Bennet and colleagues also make an important

  2019-06-28

  

  Bennet and colleagues also make an important addition to the literature on the Affordable Medicines Facility—malaria (AMFm) intervention, since a comparison of ACT treatment coverage for countries that had the AMFm intervention is made with those for countries that did not have the AMFm intervention

• We used MRI images taken to weeks after a crisis

  2019-06-28

  

  We used MRI images taken 1 to 8 weeks after a crisis to explore basal ganglion involvement and found restricted casein kinase 2 at the basal ganglion. This finding suggests that cytotoxic damage to the basal ganglion persists post-crisis. When MRI images were obtained much longer after crisis, rest

• Chronic myelomonocytic leukemia has been reported as the mos

  2019-06-28

  

  Chronic myelomonocytic leukemia has been reported as the most prevalent concomitant hematological neoplasm, followed by myelodysplastic, myeloproliferative syndrome, and acute myeloid leukemia; on the other hand, Lymphoproliferative neoplasms were less frequency associated with SM-AHMND. In another

• The multivariable Cox regression model also showed that pati

  2019-06-28

  

  The multivariable Cox regression model also showed that patients who were divorced, separated, or widowed had a significantly worse outcome than patients who were married or single; the mortality rate for Divorced, Separated or Widowed PLB patients was estimated to be 1.4 times that for married pati

• Conflict of interest br Authors contributions br Acknowledgm

  2019-06-27

  

  Conflict of interest Authors׳ contributions Acknowledgments This work was supported by grants from the Associazione Italiana Lotta alle Leucemie, Linfoma e Mieloma (AIL) – Sezione ‘Luciano Pavarotti’ Modena-ONLUS (to FF and LP) and from the Associazione Italiana per la Ricerca sul Cancro (AIR

• br History of cholesterol and bile acid research

  2019-06-27

  

  History of cholesterol and bile BAY 61-3606 research Bile is a yellow, brownish, or olive-green liquid that is composed primarily of water, organic solutes (such as lipids), inorganic salts, and some proteins. In bile, cholesterol, phospholipids, and bile acids are three major lipids, and bile pi

• br Imagine providing care for low birthweight

  2019-06-27

  

  Imagine providing care for 900 000 low birthweight (LBW; lighter than 2500 g) newborn babies each year in sub-Saharan Africa—all attributable to preventable and treatable malaria. Many of these LBW babies will be born in rural and impoverished settings where access to health care is poorest and th

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