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In the last and the most challenging part
2019-07-22
In the last and the most challenging part, three mixtures were selected to evaluate the reliability of the presented correlation and the CPA model. For Athabasca bitumen, Amani et al. [25] measured the experimental data at very high temperatures compared to the thermal recovery range up to 644 K (ne
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The heterogeneity among studies that investigated the
2019-07-22
The heterogeneity among studies that investigated the association of COMT Val158Met with alexithymia was also significant (Ham et al., 2005; Min et al., 2016; Swart et al., 2011; Zekioglu et al., 2014). The healthy status, drug effect, and other demographic variables also influenced one\'s ability o
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Our study demonstrates that the duration of storage under
2019-07-22
Our study demonstrates that the duration of storage under the conditions analysed did not have a major effect on the recovery efficiency for any of the swabs (Fig. 1). However, up to 4-fold differences in the recovery efficiencies were observed between the different swabs tested (Fig. 2). Using the
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Among the different factors that modulate Schwann
2019-07-22
Among the different factors that modulate Schwann cell biology, several studies pointed out the role played by neuroactive steroids, in particular progesterone (P4) and its derivatives dihydroprogesterone (DHP) and allopregnanolone (ALLO). Schwann ahr inhibitor are steroidogenic, possessing the ent
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br STAR Methods br Acknowledgments We thank members of R
2019-07-22
STAR★Methods Acknowledgments We thank members of R.L. lab and F. Schweisguth for critical reading of the manuscript. We are also grateful to F. Janody, M. Miura, C. Bökel, H.D. Ryoo, G. Jiménez, the Bloomington Drosophila Stock Center, the Drosophila Genetic Resource Center, the Vienna Drosoph
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Mammalian cells contain significant amounts
2019-07-19
Mammalian cells contain significant amounts of a relatively lesser known enzyme that shows marked specifity for ether lipids containing AA and other 20–22 carbon fatty acids. This enzyme is called CoA-independent transacylase (CoA-IT), and transfers polyunsaturated moieties of 20–22 carbons, typical
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Some authors rather than using
2019-07-19
Some authors, rather than using magnetic NPs as heat sources, have enhanced the activity of the linked enzymes by applying low frequency AMF. Magnetic energy is converted into a rotational motion of the enzyme-particle system that increase the collision rate with the substrate [14], [15], or trigger
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When six chemical inhibitors were incubated with
2019-07-19
When six chemical inhibitors were incubated with TRB or TRC and human liver microsomal preparation, HLM2, the results showed that ketoconazole (a CYP3A4 inhibitor) was very effective in inhibiting 4β-C hydroxylation of TRB and TR, whereas sulfaphenazole (a CYP2C9 inhibitor) and quinidine (a CYP2D6 i
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OHC is a potent regulator of LXR mediated pathways that
2019-07-19
25-OHC is a potent regulator of LXR-mediated pathways, that impact on Caspase-8, human recombinant protein chemical lipid homeostasis [8]. This oxysterol affects expression of the cholesterol efflux pumps ATP-binding cassette transporter (ABC)A1 [9] and ABCG1, and expression of apolipoprotein E [10]
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To date many studies have reported
2019-07-19
To date, many studies have reported significant aberrant methylation patterns in TIMPs in various types of cancer Cinobufagin to [[16], [17], [18]]. However, little has been reported on the events that lead to the methylation of TIMPs in the UV-irradiated human skin. Therefore, the objective of thi
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Structural characterization of A S Given the low
2019-07-19
Structural characterization of A1S_0222. Given the low specific activity of our protein preparations and the considerable problems to concentrate the protein to levels above 2.5 mg/mL, we employed SAXS to structurally characterize and generate a low-resolution model of A1S_0222 in solution. Fig. 5 a
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br Use of recombinant collagen to study
2019-07-19
Use of recombinant collagen to study DDR–collagen interactions Synthetic peptides have proven highly valuable in replicating the characteristics of collagen and in defining the sites on collagen essential for binding and studying protein–collagen interactions. There are, however, disadvantages to
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br Materials and methods br Results and discussion br
2019-07-19
Materials and methods Results and discussion Conclusions Clitocypin is another member of the mycocypin family of cysteine protease inhibitors that is unique to Fmoc-Arg(Pbf)-OH to shown to exhibit strong insecticidal activity against Colorado potato beetle larvae. This effect is concentrati
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The cyclin dependent kinase deactivation is
2019-07-19
The cyclin-dependent kinase deactivation is carried out by a particular group of proteins cyclin-dependent kinase inhibitors (CDKIs). These group of proteins blocks kinase activity by interfering with the interaction of cyclin-CDK complex [43]. The inhibition of CDK naturally occurs during a G1 phas
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br Experimental section br Notes br PDB ID codes The
2019-07-18
Experimental section Notes PDB ID codes The atomic coordinates and structure factors of hDHODH in complex with compounds 4 (PDB id: 5MVC), 5 (PDB id: 5MVD) and 6 (PDB id: 5MUT) have been deposited in the RCSB Protein Data Bank. Acknowledgements This research was financially supported by
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