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Real exchange rate is positively significant only in
2018-10-25
Real exchange rate is positively significant only in case of China and it has no effect on FPI volatility in case of remaining three countries. China is not trading in primary goods so fluctuation in exchange rate does not exist, so RER has significant positive effect on portfolio investment volatil
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To develop an effective cell based
2018-10-24
To develop an effective cell-based therapy against neurodegenerative disorders of the CNS, efficient recruitment of the cells into the CNS is essential. Previous findings suggest that particular bone marrow derived cells are able to cross the blood–brain barrier (Lebson et al., 2010; Simard and Rive
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Telomerase reactivation is a characteristic
2018-10-24
Telomerase reactivation is a characteristic of successful reprogramming to pluripotency and important for self-renewal in ESCs (Batista et al., 2011; Marion et al., 2009b). We attempted to suppress telomerase activity in WS iPSCs using the same BIBR 1532 concentration in WS-MSCtert. However, telomer
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ruthenium red Supplier Our results suggest several open ques
2018-10-24
Our results suggest several open questions that will require further investigation. Although evidence suggests that eradication of cancer stem ruthenium red Supplier appears to be beneficial for curing cancers, recent studies also suggest that noncancer stem cells acquire a cancer stem cell phenotyp
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Mass spectrometry MS based proteomics
2018-10-24
Mass spectrometry (MS)-based proteomics is a powerful approach for the comparative analysis of protein pikfyve inhibitor between cell populations. Global approaches have been used to define the MSC proteome (Delorme et al., 2008; Mareddy et al., 2009; Mindaye et al., 2013a, 2013b) and to track the
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Previously in vitro studies of CIPN were
2018-10-24
Previously, in vitro studies of CIPN were performed in rat pheochromocytoma or SK-N-SH human neuroblastoma cell lines as model systems to evaluate decreases in neurite outgrowth in response to neurotoxic chemotherapy drugs, such as paclitaxel, vincristine, oxaliplatin and cisplatin (Rovini et al.,
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Due to the lack of reliable antibodies the
2018-10-24
Due to the lack of reliable antibodies, the homozygous knockout was verified by reverse transcription and qPCR analyses of different KLF15 locus regions. This revealed the anticipated absence of transcripts encoding for KLF15 (n=8 different passages). GAPDH was equally expressed and used for normali
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Several previous studies support the possibility
2018-10-24
Several previous studies support the possibility that RPC differentiation into podocytes may be involved in remission of different types of diseases, including proliferative glomerulonephritis (Rizzo et al., 2013), gestational pre-eclampsia (Penning et al., 2014), and diabetic nephropathy (Pichaiwon
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br Introduction Neural tube defects NTDs
2018-10-24
Introduction Neural tube defects (NTDs) are still poorly understood, especially for human and non-human primates (NHPs) (Wallingford et al., 2013). In rhesus monkeys, at embryonic day 19–20 (E19–20), the neural tube (NT) contains multiple pseudostratified layers of neuroepithelial stem cells (NES
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Taken together these findings indicate that
2018-10-24
Taken together, these findings indicate that basal-to-luminal differentiation can occur in prostate organogenesis, pathogenesis, and ex vivo assays, but rarely during normal tissue homeostasis. Thus, it has been unclear to what extent the plasticity of endogenous adult prostate basal hedgehog pathwa
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A better understanding of pluripotent state
2018-10-24
A better understanding of pluripotent state of zebrafish embryos allows us to accurately induce differentiation to cardiomyocytes from primary embryonic cells. A central feature of our method is the use of a combination of appropriate conditions including cell density, ZF4 feeder cells, and suppleme
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In line with their estrogen
2018-10-24
In line with their estrogen responsiveness and activation of the 12-O-tetradecanoyl phorbol-13-acetate Supplier at puberty, the CD24+ CD49fhi SCA-1+ cells were found to be enriched in TEBs. TEBs are highest in the pubertal animal and are considered the proliferative unit of the developing gland (Rus
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Here we show that CtIP a bona fide
2018-10-24
Here we show that CtIP, a bona fide regulator of DNA end resection (Huertas and Jackson, 2009; Huertas et al., 2008; Sartori et al., 2007), is upregulated during cell reprogramming, and that it is essential for this process. Similarly, CHK1 has been suggested to be pertinent to generating iPSCs (Rui
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Here we report that FH iHeps derived
2018-10-24
Here, we report that FH iHeps derived from patient-specific and genetically engineered FH iPSCs can be used to test the efficacy of two well-known medications for lowering LDL-C, statins and PCSK9 antibodies, not only in vitro but also in vivo, by engrafting FH iHeps into the liver of immunodeficien
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In the present work we synthesized
2018-10-24
In the present work, we synthesized CuO–Ag2O bimetallic oxide nanoparticles by using microwave assisted and solid state diffusion routes. Different characterization techniques were used to characterize these samples. The LPG sensing characteristics were investigated at room temperature as well as di
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