• Tension within the network could be explained

  2024-06-13

  

  Tension within the network could be explained by two potential mechanisms: the more classical contractility that is dependent on motor proteins that are pulling Viroptic filaments towards each other [10]; or contractility that is caused by disassembly of a crosslinked network of actin filaments [2]

• To better understand the pathophysiology

  2024-06-13

  

  To better understand the pathophysiology of ASDs, we would need comprehensive information on a) the functions of ASD-associated proteins in the brain, b) how mutations affect the expression level and function of these proteins, c) how mutations affect their function in neurons, and d) how changed ne

• Further evidence for ACh GABA cotransmission had

  2024-06-13

  

  Further evidence for ACh/GABA cotransmission had also been observed in the cortex. Extensive axonal arborization from cholinergic BF neurons exists throughout the cortical layers, allowing direct observation of cholinergic synaptic terminals. One study in the visual cortex of cat examined immunolabe

• br Conclusion Growth survival and invasion of

  2024-06-12

  

  Conclusion Growth, survival, and invasion of most PCs have been shown to be androgen-dependent at the onset of castration therapy [31]. Thus, castration therapy has been central to systemic therapy and remains the standard approach to PC treatment. Even after progression to a castration-resistant

• The following are the supplementary

  2024-06-12

  

  The following are the supplementary data related to this article. Funding Work in Dr. Rosell's laboratory is partially supported by a grant from La Caixa Foundation, and an Instituto de Salud Carlos III grant (RESPONSE, PIE16/00011). Work in Dr. Cao's laboratory is partially supported by the Maj

• The SKOV and SKOV TR cells

  2024-06-12

  

  The SKOV3 and SKOV3TR jak stat pathway were exposed to stepwise increased concentration of paclitaxel with or without a different concentration of autophagy inhibitor (3-MA or HCQ) to further evaluate whether suppression of autophagy affected the growth and drug sensitivity of ovarian cancer cells

• br Acknowledgments br Introduction Cancer is the leading

  2024-06-12

  

  Acknowledgments Introduction Cancer is the leading cause of mortality in the United States for those between the ages of 40–79 years, surpassing heart diseases by more than 100,000 deaths [1]. The cause of most cancer subtypes remains idiopathic and may arise out of ‘bad luck’ among otherwise

• Based on the results of studies done to

  2024-06-12

  

  Based on the results of studies done to-date, there are three characteristics that make a letrozole-based protocol attractive for use in cattle: 1) it is steroid-free, 2) it is cost-effective and requires a shorter time and fewer animal handlings than conventional methods (Table 1), and 3) it may ha

• Apelin induced G i activation has

  2024-06-12

  

  Apelin induced Gαi activation has been demonstrated as a benefiting effect on cardiac contractility [12], [38], [39], and a vasodilator activity that protects against angiotensin-II-induced cardiovascular fibrosis and atheroma [40], [41]. In contrast, stretch causes hypertrophy through diminishing G

• Previous research showed that combination

  2024-06-12

  

  Previous research showed that combination of chitosan and CAY10603 nanocrystals (CNCs) can produce coating films with superior properties (Naseri, Mathew, Girandon, Fröhlich, & Oksman, 2015). CNCs are crystalline nanometer sized rod-like particles. It has been demonstrated that antimicrobial activit

• br Prostate cancer and resistance to AR targeting treatment

  2024-06-12

  

  Prostate cancer and resistance to AR targeting treatment The AR plays a pivotal role in the development, differentiation, homeostasis and secretory function of the normal prostate (Wilson, 2011). The AR is also a key player in many phases of prostate carcinogenesis (Huggins et al., 1941, Scher an

• asa med br Author Contributions br Acknowledgments br Introd

  2024-06-12

  

  Author Contributions Acknowledgments Introduction Cerebral ischemia-reperfusion (I/R) injury is a pathological phenomenon that occurs after restoration of blood supply to asa med tissues subsequent to ischemia or hypoxia (Carden and Granger, 2000). It typically occurs after therapeutic thro

• Consideration of the rate of product formation at different

  2024-06-12

  

  Consideration of the rate of product formation at different substrate concentrations and estimation of Michaelis-Menten parameters gives some insight into the possible mechanisms underlying the observed decreases in enzyme activity. Estimates based on two-substrate concentrations lack precision and

• br Animal models of NAFLD Human research has greatly

  2024-06-12

  

  Animal models of NAFLD Human research has greatly shaped our understanding of non-alcoholic fatty liver disease, but several limitations exist in studying the disease processes in humans, such as variations in environmental exposure, pre-existing genetic risk factors, racial and ethnic difference

• br Introduction Chronic kidney disease CKD is a worldwide

  2024-06-12

  

  Introduction Chronic kidney disease (CKD) is a worldwide public health problem. This problem is even worse in socioeconomically deprived countries because lower income and social deprivation are associated with higher incidence of reduced GFR, progressive kidney function loss and end stage renal

15647 records 131/1044 page Previous Next First page 上5页 131132133134135 下5页 Last page