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Nanaomycin A The essential autophagy gene beclin BECN
2018-11-13
The essential autophagy gene beclin 1 (BECN1) is a haploinsufficient tumor suppressor (Liang et al., 1999; Qu et al., 2003; Yue et al., 2003) that is also located on the breast cancer tumor susceptibility chromosomal locus 17q21, ~150kb centromeric to BRCA1 (Aita et al., 1999). Monoallelic loss of B
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br Introduction Retinal neovascularization is the
2018-11-13
Introduction Retinal neovascularization is the most common cause of moderate to severe vision loss in all age groups; i.e., retinopathy of prematurity (ROP) in children, diabetic retinopathy in adults and age-related macular degeneration in the elderly (Andreoli and Miller, 2007; Chen and Smith,
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Similar as the rRBD protein
2018-11-13
Similar as the rRBD protein of SARS-CoV which induced high titres of protective anti-RBD antibody responses in NHPs (Wang et al., 2012), the rRBD vaccination of MERS-CoV induced effective IgG and neutralisation (±)-Nutlin-3 in our rhesus macaque model. Besides, the induced IgG and neutralisation an
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br Herpes zoster is a
2018-11-12
Herpes zoster is a benign and usually self-limiting disease, although herpes zoster has a notorious reputation among lay people because of the acute pain during an attack and because of the common myth that herpes zoster located circumferentially on the trunk is fatal. We report an unusual case of
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tlr signaling br Propionibacterium acnes P acnes an
2018-11-12
Propionibacterium acnes P. acnes, an opportunistic pathogen that plays an important role in the progression of inflammatory acne vulgaris, are ubiquitously present within the sebaceous follicles of the human skin. These acne-causing bacteria are usually gram positive, nonmotile, fat splitting mic
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br Discussion TEPD is a very rare subgroup
2018-11-12
Discussion TEPD is a very rare subgroup among EMPDs, and only a few case reports or case series have been published. This is the first reported Taiwanese case of TEPD. Most cases were reported from Japan. There was a male predominance in the patient groups. Including our case, all but one of the
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There have been increasing reports of NTM infection after ta
2018-11-12
There have been increasing reports of NTM infection after tattooing in recent years. The majority of cases are related to M. chelonae infection. M. abscessus infection after tattooing was rarely reported in the literature, as summarized in Table 1. M. abscessus infection is particularly virulent an
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br Discussion EMN is a rare phenomenon
2018-11-12
Discussion EMN is a rare phenomenon in which hundreds of melanocytic nevi appear suddenly. The lesions of EMN can include banal nevi, blue nevi, and Spitz nevi. EMN may arise in the setting of blistering skin disease, immunosuppression, cytokine administration, biological agent administration, ch
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Adipocytes are described as newly introduced members of
2018-11-12
Adipocytes are described as newly introduced members of the immune system, as they release cytokines such as interleukin 6 and TNF-α in addition to adipokines such as irisin, adiponectin, and leptin. Discovered by Boström et al, irisin is made up of 112 amino acids, and is synthesized in the muscula
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In the simulations the canards span
2018-11-12
In the simulations, the canards span freely until 5 s after launch. Fig. 9 shows the inherent vibration frequencies (include the fast and slow part) of 155 mm projectile during the entire flight domain. It can be seen from Fig. 5 when the rotation speed of the forward part is 0.5 revolutions per se
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br Experimental tests and results
2018-11-12
Experimental tests and results Discussion Table 8 shows the success of the geometric similarity measured by means of the peak pressures for the open-end blast chamber. The pressure time history ibotenic acid manufacturer invariant by geometric similarity. One of the series of tests confirmed g
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TATB based PBXs formulations such
2018-11-12
TATB based PBXs formulations such as LX-17 and PBX 9502 [18–21] have been developed for nuclear bomb, missiles and space applications. TATB has a high thermal stability, insensitive in terms of impact and friction but poor performance. The performance of formulations has been enhanced either to use
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s ibuprofen These countries are selected based
2018-11-12
These countries are selected based on data availability on private consumption and exchange rate. This paper contributes to existing literature by exploring the effect of exchange rate volatility on private consumption in sub-Saharan African countries. The study focuses on only sub-Saharan African c
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Introduction br History br Conservation projects and assessm
2018-11-12
Introduction History Conservation projects and assessments Characteristics of conservation Issues Conclusion Introduction Methodology Results and analysis Conclusion Acknowledgements This study is supported by the Ministry of Science and Technology of China (Project nu
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Efforts in limiting CO emissions from buildings concentrate
2018-11-12
Efforts in limiting CO2 emissions from buildings concentrate on energy demand reduction. As fossil fuels still represent the bulk of energy sources used, reducing energy demand reduces carbon emissions. Another approach is to provide energy from renewable sources like sun, wind and biomass. Little c
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